Articles

Nutrition for endometriosis: A guide to manage symptoms.

What is Endometriosis?

Endometriosis is a complex chronic systematic inflammatory gynecological disease. Characterized by the ectopic implantation of the functional tissue of the uterus, (outside the uterine cavity). Leading to pain, inflammation, and various symptoms that can significantly impact quality of life.

Endometriosis affects approximately of 10 % women of reproductive age worldwide, 2-4% of perimenopausal women, and up to 50% of infertile women. 

What are the symptoms of endometriosis?

- Pelvic pain.

- Painful periods (dysmenorrhea)

- Heavy menstrual bleeding.

- Painful urination (dysuria).

- Painful defecation (dyschezia).

- Irritable bowel syndrome (IBS) symptoms, such as constipation and/or diarrhea and abdominal discomfort

- Fatigue.

- Depression.

What are the possible causes of endometriosis?

It is thought that immune system disorders, hormonal imbalances, and genetic predispositions worsen the condition, though the precise cause is still unknown.

 What is the treatment of endometriosis?

While there's no one-size-fits-all solution, treatment can be divided into two categories: pharmaceutical treatments that try to stop the growth, surgical treatments that try to remove the endometriotic implants, nutrition can play an essential role in managing symptoms, and improving quality of life for women who are suffering from endometriosis.

 Increasing attention is being paid to how nutrition can influence the course of the disease. Proper nutritional strategies can help reduce inflammation, balance hormones, and improve overall well-being for those living with endometriosis.

It has been found that certain diets can help reduce some symptoms

1)    Anti-Inflammatory Diet: Reduces the symptoms.

2)    |Mediterranean Diet: Has an anti- inflammatory role, which also helps in reducing the symptoms.

3)    High fiber Diet: Increases the microbiome diversity which leads to down regulation of Mast cells and decreases inflammation.

What nutrients to focus on?

·       Antioxidants: (such as resveratrol, anti-inflammatory agents (composed of vitamins, minerals, probiotics, and fish oil), and anti-proliferative compounds (such as garlic). Dietary supplementation was found to reduce dysmenorrhea while having no effect on pelvic pain.

·       Fiber-Rich Foods: Clinical interest has grown in the possible anti-inflammatory benefits of plant-based diets. Because vegetables and fruits contain bioactive plant compounds like polyphenols, phytoestrogens, resveratrol, and vitamin C, a number of studies have demonstrated the health benefits of eating a diet rich in these foods.

·       Healthy Fats: Include sources of healthy fats, such as avocados, olive oil, and nuts. These can be beneficial for hormone regulation and overall health.

·       Omega-3 Fatty Acids: Incorporate sources of omega-3s like fatty fish (salmon, mackerel), chia seeds, walnuts, and flaxseeds. Omega-3s can help lower inflammation and may alleviate pain.

 

What foods and nutrients to limit or avoid?

·       Avoid Processed Foods.

·        Limit sugar.

·        Refined carbohydrates.

·       Trans fats.

·       Red meat.

·       Dairy products.

Which can increase the risk of endometriosis or, exacerbate inflammation.

What supplements are recommended?

·       Vitamins (C, D, and E): They have role in reducing inflammation and reducing pain.

·       Calcium: symptoms managing and reducing inflammation.

·       - Curcumin: The active compound in turmeric, known for its anti-inflammatory properties.

·       Magnesium: Can help relieve menstrual cramps and improve overall mood.

·       Polyphenols: Anti-inflammatory role.

How water intake can help in endometriosis?

Hydration and endometriosis are connected in several ways such as:

·       Inflammation reduction: proper hydration helps in decreasing inflammation, which can alleviate some symptoms.

·       Detoxification: adequate water intake aids the body natural detox processes that help in reducing endometriosis symptoms.

·       Improves circulation: staying well-hydrated enhances blood flow, promoting better oxygen and nutrient delivery to the affected pelvic tissue.

·       Alleviate pain: hydration can help reducing pain by relaxing uterine muscles and preventing muscle spasms.

·       Assists proper digestion and absorption: proper hydration supports digestive health, which can influence hormonal balance.

·       Promotes overall well-being: good hydration contributes to improved energy levels, mood, and immune response, all beneficial for managing endometriosis symptoms.

 

Lifestyle Factors:

·       Regular Exercise: Physical activity can help manage weight and reduce the severity of symptoms by aiding hormone regulation.

·       Stress Management: Techniques such as yoga, meditation, and deep breathing exercises can be beneficial, as stress can exacerbate symptoms.

·       Adequate Sleep: Prioritizing good sleep is essential for overall health and can help manage stress levels.

·       Developing a Personalized Plan: Every individual’s experience with endometriosis is unique, so working with a healthcare professional—such as a registered dietitian or a physician who specializes in endometriosis—is crucial. They can help tailor a nutrition plan based

on individual symptoms, health history, and preferences.

Conclusion

While nutrition alone won't cure endometriosis, it can be a powerful tool for managing symptoms and improving overall well-being. By focusing on anti-inflammatory foods, maintaining a balanced diet, and incorporating healthy habits, endometriosis patients can take proactive steps towards better management of their condition. Always consult with a healthcare professional before making significant dietary changes.


References:

  • Tsamantioti ES, Mahdy H. Endometriosis. [Updated 2023 Jan 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-
  • Neri, L. C. L., Quintiero, F., Fiorini, S., Guglielmetti, M., Ferraro, O. E., Tagliabue, A., Gardella, B., & Ferraris, C. (2025). Diet and Endometriosis: An Umbrella Review. Foods (Basel, Switzerland), 14(12), 2087.
  • Abulughod, N., Valakas, S., & El-Assaad, F. (2024). Dietary and Nutritional Interventions for the Management of Endometriosis. Nutrients, 16(23), 3988.
  • Barnard, N. D., Holtz, D. N., Schmidt, N., Kolipaka, S., Hata, E., Sutton, M., Znayenko-Miller, T., Hazen, N. D., Cobb, C., & Kahleova, H. (2023). Nutrition in the prevention and treatment of endometriosis: A review. Frontiers in nutrition, 10, 1089891.
  • Nap, A., & de Roos, N. (2022). Endometriosis and the effects of dietary interventions: what are we looking for?. Reproduction & fertility, 3(2), C14–C22.
  • Huijs, E., & Nap, A. (2020). The effects of nutrients on symptoms in women with endometriosis: a systematic review. Reproductive biomedicine online, 41(2), 317–328.
  • Martire, F. G., Costantini, E., d’Abate, C., Capria, G., Piccione, E., & Andreoli, A. (2025). Endometriosis and Nutrition: Therapeutic
  • Perspectives. Journal of clinical medicine, 14(11), 3987.
  • Habib, N., Buzzaccarini, G., Centini, G., Moawad, G. N., Ceccaldi, P. F., Gitas, G., Alkatout, I., Gullo, G., Terzic, S., & Sleiman, Z. (2022). Impact of lifestyle and diet on endometriosis: a fresh look to a busy corner. Przeglad menopauzalny = Menopause review, 21(2), 124–132. https://doi.org/10.5114/pm.2022.116437